142–9.įranchitto N, Minville V, Dédouit F, Telmon N, Rougé D. Amniotic fluid embolism, pulmonary embolism. Amniotic fluid embolism: an evidence-based review. Hyperfibrinolysis diagnosed by rotational thromboelastometry in a case of suspected amniotic fluid embolism. A hypothesis regarding complement activation and amniotic fluid embolism. 2010 197:1Ĭunnigham FG, Leveno KJ, Bloom SL, Spong CY, Dashe JS, Hoffman BL, Casey BM, Sheffield JS. Amniotic fluid embolism, Anesthesia tutorial of the week.
Amniotic fluid embolism after blunt abdominal trauma. Amniotic fluid embolism: decreased mortality in a population-based study. Early and aggressive resuscitation is essential for maternal and neonatal survival. Collapse of the cardiovascular system leads to fetal distress and death unless the child is delivered swiftly. The blood loses its ability to clot and there is excessive bleeding. Not long after this stage, the patient will lose consciousness due to circulatory collapse leading to death of mother unless managed on war footing.Ībout 40% of the initial survivors will pass onto the hemorrhagic phase after left heart failure.
This rapidly progresses to cardiac failure because of pressure overload leading to a reduction of perfusion to the heart, lungs, and finally brain. In the first phase, the patient experiences acute shortness of breath due to pulmonary hypertension. Patient presents clinically in the following phases: The pathogenesis of AFE is complicated and not clear its development envisages mechanical obstruction of the pulmonary vessels by amniotic fluid components to humoral and immunological factors.Įntrance of amniotic fluid to maternal circulation: It specifically occurs during labor and delivery or immediate postpartum usually either within 5 min or 48 h postpartum or during blunt abdominal trauma or procedures like cervical suture removal and transabdominal amniocentesis during pregnancy.Ĭesarean or assisted delivery procedures (forceps, vacuum) Amniotic fluid embolism is an obstetric emergency in which amniotic fluid, fetal cells, hair, or other debris enters mother’s bloodstream through placental bed and thereby initiates allergic reaction resulting in cardiopulmonary collapse, respiratory compromise, and coagulopathy leading to massive hemorrhage.ĪFE is classically characterized by a triad of hypoxia, hypotension, and consumptive coagulopathy.
0 kommentar(er)
